| 08/18/2022 | at Akron | L | 0-1 | 0-1-0, 0-0-0 | 0-0-0 | 250 | |
| 08/21/2022 | at Valparaiso | L | 0-1 | 0-2-0, 0-0-0 | 0-0-0 | 247 | |
| 08/25/2022 | vs Duquesne | L | 1-2 | 0-3-0, 0-0-0 | 0-0-0 | 358 | Maddie Root (1) (Abby Knight)
|
| 08/28/2022 | at Loyola Maryland | L | 0-4 | 0-4-0, 0-0-0 | 0-0-0 | 162 | |
| 09/01/2022 | at St. Bonaventure | T | 0-0 | 0-4-1, 0-0-0 | 0-0-0 | 75 | |
| 09/04/2022 | vs Bucknell | W | 1-0 | 1-4-1, 0-0-0 | 0-0-0 | 245 | Regan LaVigna (1) (Haley Curtis)
|
| 09/08/2022 | vs Kent St. | W | 1-0 | 2-4-1, 0-0-0 | 0-0-0 | 327 | Lily Welch (1) (Lianna Van Sice)
|
| 09/15/2022 | at Oakland | T | 1-1 | 2-4-2, 0-0-1 | 0-0-1 | 216 | Taylor Berry (1) (Regan LaVigna)
|
| 09/18/2022 | vs Wright St. | L | 0-2 | 2-5-2, 0-1-1 | 0-1-1 | 326 | |
| 09/22/2022 | at Detroit Mercy | L | 0-1 | 2-6-2, 0-2-1 | 0-2-1 | 101 | |
| 09/25/2022 | vs Milwaukee | T | 1-1 | 2-6-3, 0-2-2 | 0-2-2 | 258 | Jordan Evans (1) (Mikayla Mustard)
|
| 10/06/2022 | vs Green Bay | W | 3-0 | 3-6-3, 1-2-2 | 1-2-2 | 357 | Elis Spindola (1) (Regan LaVigna , Abriana Rondin) Abriana Rondin (0) Justine Appolonia (1) (Elis Spindola , Emma Rignone)
|
| 10/09/2022 | at Northern Ky. | W | 1-0 | 4-6-3, 2-2-2 | 2-2-2 | 274 | Elis Spindola (2)
|
| 10/13/2022 | vs Purdue Fort Wayne | W | 1-0 | 5-6-3, 3-2-2 | 3-2-2 | 435 | Abriana Rondin (2) (Taylor Berry)
|
| 10/16/2022 | at Cleveland St. | L | 2-4 | 5-7-3, 3-3-2 | 3-3-2 | 320 | Mikayla Mustard (1) Regan LaVigna (2) (Haley Curtis)
|
| 10/22/2022 | vs IUPUI | W | 2-0 | 6-7-3, 4-3-2 | 4-3-2 | 326 | Regan LaVigna (3) (Abriana Rondin , Haley Curtis) Taylor Berry (2)
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| 10/26/2022 | at Robert Morris | W | 3-1 | 7-7-3, 5-3-2 | 5-3-2 | 117 | Elis Spindola (5) (Haley Curtis , Marissa Masano) Elis Spindola (5) (Regan LaVigna) Elis Spindola (5) (Marissa Masano)
|
| 10/30/2022 | at Wright State | W | 2-1 | 8-7-3, 5-3-2 | 5-3-2 | 514 | Taylor Berry (3) Taylor Berry (3)
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| 11/03/2022 | at Purdue Fort Wayne | W | 1-0 | 9-7-3, 5-3-2 | 5-3-2 | 573 | Abriana Rondin (3)
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| 11/05/2022 | at Milwaukee | L | 0-1 | 9-8-3, 5-3-2 | 5-3-2 | 335 | |